Is B12 Level Of 1500 Too High?

Can fatty liver cause high B12 levels?

The levels of vitamin B12 were correlated with the stage of NAFLD, lipid profile and liver parameters.

Results: Vitamin B12 levels were significantly lower in patients with NAFLD.

Vitamin B12 levels inversely correlated with cholesterol and triglyceride levels..

What does high B12 mean in blood test?

Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin.

Can Vitamin B12 damage your liver?

Some studies have indicated that elevated serum levels of vitamin B12 might be a sign of a serious and life-threatening disease. Such falsely high valued of serum vitamin B12 levels are observed in myeloproliferative disease, acute hepatitis, severe alcoholic liver disease, and cirrhosis.

Does high B12 mean deficiency?

Deficiency should be confirmed by checking the level of a substance in the blood called methylmalonic acid. A high level indicates a true B12 deficiency. Causes of vitamin B12 deficiency include: Not enough vitamin B12 in diet (rare, except with a strict vegetarian diet)

What is normal level of vitamin B12 in elderly?

A serum vitamin B12 level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly. The laboratory diagnosis is usually based on low serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels.

Is B12 level of 1100 too high?

The normal range for vitamin B12 (total) is between 200 – 1100 ng/L (nanograms per liter), 200 – 1100 pg/mL (picograms per milliliter), or 148 – 811 pmol/L (picomoles per liter). The normal range for active vitamin B12 (holoTC) is around 20 – 134 pmol/L (picomoles per liter).

What is a good level of vitamin B12 in blood?

But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.

Is B12 level of 1000 too high?

Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10. Excess B12 is either stored in the liver, present in the blood without any adverse effects, or excreted.

How do I lower my B12 levels?

You can change your diet to include vitamin B12-fortified grains, a supplement or B12 injections, or a high-dose oral vitamin B12 if you are deficient. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12.

Should I be worried if my B12 is high?

Though daily high doses of B12 are unlikely to cause harm in most people, extremely high doses should be avoided unless prescribed by a healthcare professional. If you think you may be deficient in B12, speak with your doctor, who can recommend an appropriate treatment based on your level of deficiency.

Why is my B12 over 2000?

The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don’t worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.

What causes high B12 and folate levels in blood?

However, if someone has a condition such as chronic myeloproliferative neoplasm, diabetes, heart failure, obesity, AIDS, or severe liver disease, then that person may have an increased vitamin B12 level. Ingesting estrogens, vitamin C or vitamin A can also cause high B12 levels.

Can you have pernicious anemia with high B12 levels?

A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.

Can stress cause high B12 levels?

What is the relationship between vitamin B12 and stress? The fact is, high levels of stress can deplete your body of B vitamins, which are essential for the nervous and circulatory systems.

What can cause false high B12?

Low vitamin B12 levels can be measured as false normal or false high, especially in pernicious anemia, due to excessive amounts of anti-intrinsic factor antibodies present in the serum [5,6,7].

What happens if Vitamin B12 is high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

How long does it take to get rid of excess B12?

If a person stops consuming the vitamin, the body’s stores of this vitamin usually take about 3 to 5 years to exhaust. People should not take high doses of vitamin B12 as a cure-all, but otherwise the vitamin does not appear to be toxic; consuming excess amounts of B12 is not recommended.